NIH Complement Animal Research in Experimentation NAMs Reduction to Practice Challenge

Develop human-based new approach methodologies (NAMs) – including lab-based human cell systems, computer models, and biochemical assays.

Apply to develop human-based non-animal methods – including lab-based human cell systems, computer models, and biochemical assays –  that can be turned into a practical, working solution within three years. 

Key information
Sponsoring agencyNational Institutes of Health (NIH)
Start date09/25/2025 11:59 ET (Phase 1)
End date3/1/2026 11:59 ET (Phase 1)
Challenge typeTechnology
PrizesTotal cash prizes: $7,000,000
ContactHuLC@nianet.org

Apply for the NIH Complement Animal Research in Experimentation NAMs Reduction to Practice Challenge

These federal prize competitions are conducted pursuant to the America COMPETES Reauthorization Act of 2010, as amended by the American Innovation and Competitiveness Act of 2017. For complete rules, eligibility requirements, and terms and conditions, please visit the hosting agency's competition page.

LAST UPDATED: February 18, 2026

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