Browse active challenges from the government

Help family caregivers and the caregiving industry improve care quality and reduce burden through artificial intelligence (AI).

Create comics to help reduce health risks and pressure to meet society’s beauty standards.

Drive new ideas for how to identify and trace modified biological sequences, such as proteins, genes, and genomes.

Help strengthen the connections between learners, educators, training providers, and employers by fostering the development of integrated Talent Marketplaces.

Help transform heavy-lift aviation. Submit your drone design that can carry a payload more than four times its own weight.

Support NASA's small satellite (smallsat) missions with hardware, software, or hybrid AI-driven solutions.

Develop human-based new approach methodologies (NAMs) – including lab-based human cell systems, computer models, and biochemical assays.

High school students: showcase your understanding of civics and knowledge of America’s founding.

Develop programmable delivery systems and non-viral delivery across the blood-brain barrier.

Help find innovation technology solutions for the U.S. Army to address critical capability gaps.